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In: Biology

What is an advantage of an enzyme with multiple domains each with a different catalytic site?

What is an advantage of an enzyme with multiple domains each with a different catalytic site?

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Expert Solution

If an enzyme is having multiple domain, each with a different catalytic site, it means that the enzyme can bind to more than one types of substrate at one time.

This is particularly important during condensation or anabolic reaction. In these reactions, water, one or more than one types of monomers are used for the synthesis of polymers. So, at one time, the enzyme can bind to all the different types of monomers and water and thereby synthesizing polymers.

Apart from binding substrate molecules, this domain are also responsible for binding cofactors and activator proteins. These accessory molecules help in increasing the rate of catalytic reaction.

Sometime inhibitor and repressor molecules can also bind to this site thereby decreasing the rate of reaction.

Hence, the overall advantage of having multiple domain in enzyme is to bind more than one type of substrate at one time and also to bind activator in order to increase the rate of reaction.

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