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In: Biology

Describe why shape is critical to the proper functioning of all proteins.

Describe why shape is critical to the proper functioning of all proteins.

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Expert Solution

Each protein has its own unique sequence of amino acids and the interactions between these amino acids create a specify shape. The amino acid sequence causes the polypeptide to assume a particular shape. The shape of a protein determines its specific function. The correct amino acid sequence is determined by the cell's genetic information. The slightest change in this sequence may affect the protein's ability to function. Some are globular (roughly spherical) in shape, whereas others form long, thin fibers. For example, the hemoglobin protein that carries oxygen in the blood is a globular protein, while collagen, found in our skin, is a fibrous protein. Many different types of chemical bonds may be important in maintaining this shape. Changes in temperature and pH, as well as the presence of certain chemicals, may disrupt a protein’s shape and cause it to lose functionality, a process known as denaturation. This shape determines the protein's function, from digesting protein in the stomach to carrying oxygen in the blood.


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