Question

Create a table of the following Cardiovascular and Systemic Diseases:

4) Tularemia

5) Toxoplasmosis

6) Plague

7) Dengue fever

8) Infectious Mononucleosis

9) Ebola

10) Lyme disease

11) Cytomegalovirus Disease

Create columns as shown below:

Name of Disease	Causative Agent(s)	Common Mode of Transmission	Pathogenesis and Virulence factors	Epidemiology	Prevention and Treatment

Answer 1

Name of Disease	Causative Agent	Common mode of Transmission	Pathogens and Virulence Factors	Epidemiology	Prevention and Treatment
Tularemia	Gram negative cocobacillus Francisella tularensis	- during handling the infected animals, -ingestion of contaminated food or water, -inhalation of infective aerosols and arthropod bites.	Type IV secretion system, ATP binding cassette proteins 23 KD protein named as IgIC	Tularemia is mainly reported in the northern hemisphere. It is also reported in the Middle East hemisphere of the world.	Prevention is to stay away from infected rabbits and rodents or any other reservoirs known to be infected. Treatment = Antibiotics such as Streptomycin, Gentamycin Tetracyclin, Chloramphenicol or Fluoroquinolones.
Toxoplasmosis	Single cell parasite Toxoplasma gondii	Transmission by = ingestion of raw or inadequately cooked infected meat. contact with cats and their faeces.	TgHSP70 ROP18	The 22.5% of the United States population over age 12 is infected with this disease. In other countries, the percentage of infection is between 30 to 95%.	Prevention = by cooking food at standard safe temperature. fruits should be washed. Treatment = Antibiotic = sulphadiazin. Folic acid with pyrimethamine
Plague	Yersinia pestis	Transmission: Plague is transmitted from rodents to human by the bite of an infected flea. through respiratory droplets from infected people	Endotoxin associated with lipopolysaccharides (LPS). Presence of plasmid which gives the bacterium the ability to develop resistance to antibiotics.	The outbreak of Plague results into pandemics which spreads upto Egypt, Mediterranean, Europe, West coast of the United States.	Prevention = by making home and surrounding area rodent proof. by wearing gloves to prevent contact between skin and plague bacteria during handling of infected animals Antibiotics such as Strptomycin, Gentamycin, Doxycycline or Ciprofloxacin.