Question

1.Describe the difference between drug dependence and drug tolerance

Answer 1

Features	Drug Dependence	Drug Tolerance
Defination	Dependence specifically refers to a physical condition in which the body has adapted to the presence of a drug to attain a certain Effect.	It is defined as a person’s diminished response to a drug that is the result of repeated use.
Withdrawal Symptoms	Seen if Individuals Stops Taking Drugs All of A Sudden For Example patient will Experience- Irritability Joint pain Tremors Disturbed sleep Weakness Fatigue	Not seen with the Drugs that Cause Tolerance
Developed	Mostly in illicit Drugs but also in Certain Prescibed medications.	Both illicit Drugs and prescription Medications.
Addiction	Can be Seen	Not Seen
Types	There are 2 types of Drug Dependence- Physical Dependence- It means that the body has developed a physiological reliance on a drug because it has caused changes in its natural state of being. Examples- Opiates, tobacco, and alcohol Psychological dependence affects a person emotionally and mentally. This develops from the memory of the sense of euphoria that the drug creates, causing a person to long for that feeling and think of it often. Examples- Cocaine and Amphetamines.	Acute tolerance occurs over a relatively short period of time. Example- Cocaine Chronic or long-term tolerance occurs when an individual’s body adapts to the effects of a drug under constant exposure over a long period of time, such as weeks or months. Learned tolerance can result from exposure to certain addictive substances such as alcohol.
Treatment	Can Be done Medically along With Detox Programs. For Example- Steroid Tolerance can be treated by Tapering the Drug dose Slowly.	Can be Done Medically. For Example Opoid Tolerance Can Be Dealth With- alpha2-adrenoreceptor agonists such as clonidine and NMDA antagonists such as ketamine or dextromethorphan have been Used.