Question

17) Refer the previous question: The following table gives the common disorders, problems and complaints associated with each body system and its components relevant to the nursing care you might provide for your clients in the Australian health care system. Complete the following table with regard to its definition, pathophysiology, signs and impact of specific health procedures(in 10-20 words each). DISEASES AFFECTING THE MUSCULOSKELETAL SYSTEM Gout Gout

17.1) Definition Minimum word required : 10 Word count

17.2) Briefly outline the pathophysiology Minimum word required : 10 Word count

17.3) List four specific signs Minimum word required : 10 Word count

17.4) Impact of allopurinol on patients with gout. Minimum word required : 10

Answer 1

Answer

17.1) Definition Minimum word required : 10 Word count

Gout is a metabolic disorder of Purin metabolism ,characterized by intermittent attach of acute pain swelling and inflammation.

It is always preceded by hyperuricemia.

17.2) Briefly outline the pathophysiology Minimum word required : 10 Word count.

Due to increased uric acid production and less elimination result increased uric acid in the blood stream and it may combined with sodium and which may produce sodium crystals(tophi),it is deposited over the soft tissues and joints which result inflammation in the articular surface and release of indomethacin,it may cause infiltration granulocytes that phagocytes urates crystales and release of Cholchcine and release of free radicals it may result free radical damage tissue and release of proteolytic enzyme glycoprotein it produce lactic acid and cholchicine which result release of lysosomal enzymes it damage the joints by destruction.

17.3) List four specific signs Minimum word required : 10 Word count

1.Gouty arthritis is one of the common manifestations ,it include involvement of one or more joint swelling develop great toe followed by other joints like ankle,knee,wrist,...

2.Join are tender,cynotic

3.Sudden swelling and excruciating pain

4.Low grade fever usually subsides with in 2-10days.

17.4) Impact of allopurinol on patients with gout. Minimum word required : 10

The allopurinol is the drug of choice in acute and chronic Gout the main mechanism of action is uric acid synthesis inhibitors,it works on the prevention of uric acid synthesis by inhibiting the enzyme xanthaine oxidase which may result reduce plasma uretate levels ,and it promote the excretion of xanthaine and hypoxanthine excretion by urine their by the blood uric acid level is reduced.so the allopurinol considered an effective impact on Gout.