Answer - The roles of thiamin, riboflavin, and niacin in energy
metabolism and other body functions------
- (1)-Thiamin, riboflavin, niacin are required for
decarboxylation, transmutation, acylation, oxidation and reduction
of substrates that ultimately used in energy consumption. One or
more major of these are also important for amino acids, fatty
acids, cholesterol, steroids and glucose synthesis.
- (2) - In fact, thiamin plays a critical role in the energy
metabolism and therefore in the growth, development and function of
cell.
- (3) - Although thiamin deficiency is not usual in developed
countries, because it is contained in breads, cereals, pulses,
meat, liver, fish and some fortified foods.
- (4)- The existence of thiamin deficiency has been observed in
more than half of the elderly people who require nursing care.
- (5)-Riboflavin is an essential component of two coenzymes that
play major roles in energy production, cellular function, growth
and development, and metabolism of fat, drugs and steroids.
- (6)- Riboflavin deficiency is extremely rare in developed
countries because its sources are commonly consumed foods (milk and
milk drinks, bread and bread products, mixed foods whose main
ingredients is meat, ready to eat, cereals and bread products,
mixed foods whose main ingredients is meat, ready to eat cereals
and bread products, mixed foods whose main ingredients is meat,
ready to eat cereals and mixed foods whose main ingredients is
grain).
- (7) However, adolescents are at a high risk for nutrional
deficiencies because of their notoriously poor dietary habits, and
the estimation of riboflavin deficiency may be an indicator of the
overall nutritional status.
- (8)- The function of niacin in human body is precursor of the
nicotinamide nucleotide coenzymes NAD and NADP . NAD is essential
for energy - producing reactions and NADP for anabolic reactions.
Moreover, NAD also participates in unique non-redox adenosine
diphosphate ribose transfer reactions that are involved in protein
modification, calcium mobilization, cell signaling, and DNA
repair.
--Thiamin, riboflavin niacin are essential micronutrients are
are involved in energy metabolism, they may prevent the occurance
of devepmental abnormalities and chronic degenerative and Chornic
degenerative neoplastic disease.