A high dose treatment of osteosarcoma includes the use ofmethotrexate at a starting dose of...

A high dose treatment of osteosarcoma includes the use of methotrexate at a starting dose of 12 g/m2 given over a 4-hour IV infusion. The patient has a BSA = 1.7 m2 Calculate the grams of drug the patient would receive after 2-hours of the infusion. Round the final answer to the tenths place.

Expert Solution

Answer - Methotrexate starting dose = 12 g /m2

BSA = 1.7 m2

Dose in 4 hour = 1.7 × 12

= 20.4 gram

So In 2 hour infusion = 20.4 /2

= 10.2 gram

So patient recieve 10.2 gram Methotrexate via iv infusion in 2 hours.

Nightingale answered 2 years ago

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