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In: Biology

Create columns as shown below: Name of Disease, Causative Agent(s), Virulence factors , Pathogenesis for the...

Create columns as shown below: Name of Disease, Causative Agent(s), Virulence factors , Pathogenesis for the following skin diseases Erysipelas, and Cutaneous candidiasis.

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Expert Solution

Name of the Disease Causattive Agent Virulence factors Pathogenesis
Erysipelas - It is the skin condition (type of cellulitis) that is caused by bacterial infection. The superficial skin layers get affected (upper dermis and cutaneous lymphatics) The causative bacteria is Streptococcus pyogenes (belonging to Group A of streptococcal bacteria) The virulence factors of the bacteria are - hyaluronic acid capsule, lipoteichoic acid and M protein, pyrogenic toxinx (extracellular products), and streptolysins, streptodornase and streptokinase The spread of infection occurs rapidly in upper dermis and it invades the superficial cutaneous lymphatics very rapidly.
Cutaneous candidiasis - It is the infection of skin and nails. The infection is caused by fungus and prolonged exposure to moisture increases the risk of infection. The causative agent is Candida fungus. The most common fungus that causes cutaneous candidiasis is Candida albicans. The virulence factors include biomolecules such as adhesins that are host recognizing substances. Other virulence factors include the morphogenesis ability of the fungus, extracellularly secreted phospholipases and aspartyl proteases. It is an opportunistic infection. Cutaneous candidiasis often affects oral cavity, gastrointestine, female reproductive tract and cutaneous epithelium.

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