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What types of modifications can occur after a polypeptide chain has been completed by a ribosome?...

What types of modifications can occur after a polypeptide chain has been completed by a ribosome? (Choose as many that apply) A) Glycosylation B) Removal of methionine C) Hydrolysis D) Addition of amino acids E) Phosphorylation

Solutions

Expert Solution

Options A, B, C, and E are correct.

Explanation:

Post-translational modifications occur after the polypeptide is released from the ribosome. These modifications can occur in the cytosol or ER or Golgi.

They include

a. Phosphorylation

b. Glycosylation

c. Removal of amino acids (especially N terminal methionine) by peptide bond hydrolysis

d. Acetylation, Sumoylation etc...

gladiator answered 2 years ago
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