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QUESTION 1 A single base change mutation at the third position in a codon for a...

QUESTION 1

A single base change mutation at the third position in a codon for a protein encoding gene would most often cause a ______.

( )

Deletion mutation

( )

Insertion mutation

( )

Nonsense mutation

( )

Silent mutation

( )

Missense mutation

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QUESTION 2

Which of the following correctly ranks a point mutations effect on a protein from most severe mutation to the least?

( )

Missense, silent, nonsense

( )

Silent, nonsense, missense

( )

Nonsense, missense, silent

( )

Nonsense, silent, missense

( )

Silent, missense, nonsense

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QUESTION 3

Which statement is FALSE about the mismatch repair system?

( )

The mismatch repair system relies on the 3' exonuclease activity of DNA Polymerase III.

( )

The mismatch repair system involves the MutS/MutL/MutH proteins.

( )

The mismatch repair system recognizes which strand of the chromosome is the parent strand because it is methylated.

( )

The mismatch repair system recognizes mismatched complementary base pairs.

( )

The mismatch repair system cleaves away the mistake, DNA polymerase I fill in the gaps, and ligase  joins the backbone of newly repaired strands.

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QUESTION 4

Which of the following is NOT a method of horizontal gene transfer?

( )

Bacterial mating between two E. coli strains.

( )

Streptococcus rough cells taking up the capsule genes from dead Streptococcus smooth cells.

( )

Corynebacterium diphtheria strains bearing a toxin on a prophage.

( )

Binary fission of a Bacillus subtilis strain.

( )

All of the above are methods of horizontal gene transfer.

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QUESTION 5

The formation of a sex pilus between and F+ strain and an F- strain occurs during ____.

( )

Binary fission

( )

Conjugation

( )

Replication

( )

Transformation

( )

Transduction

Solutions

Expert Solution

Q1) Silent mutation. This is because mostly the first basis decide the amino acid and 3rd position is less significant. This is explained by Wobble hypothesis

Q2) Nonsense, missense, silent.

This is because Nonsense mutation will code for non sense codon, thus peptide chain will stop forming in midst only.

Missense mutation will change amino acid. This it is less severe as protein will be formed atleast.

Silent mutation doesnot effect the protein chain.

Q3) false-

1) The mismatch repair system relies on the 3' exonuclease activity of DNA Polymerase III. As experiments say this enzyme activity is not required . It is done by Mut proteins. Whereas the gaps can be filled by 5'-3' exonuclease activity of DNA pol3.

5)The mismatch repair system cleaves away the mistake, DNA polymerase I fill in the gaps, and ligase  joins the backbone of newly repaired strands.

As this is done by Dna pol3.

If they are asking to mark only 1 , you can mark the 1st statement only.

Q4) Binary fission of bacillus strain.

Rest all statement are of horizontal gene transfer.

1st statement shows conjugation

2nd statement shows transformation

3rd statement shows transduction via virus.

Q5) Conjugation- it is horizontal gene tramsfer using a sex pilus also klcalled conjugation tube. The conjugation tube is formed by F+ bacteria.

If I could help you. Please Hit thumbup :)

gladiator answered 2 years ago
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