What are the advantages and disadvantages of using live attenuated organisms as vaccines?

What are the advantages and disadvantages of using live attenuated organisms as vaccines?

Expert Solution

Live Attenuated vaccine is the types of vaccines, a weaker, asymptomatic form of the virus or bacteria is introduced into the body. Because it is weakened, the pathogen will not spread and cause sickness, but the immune system will still learn to recognize its antigens and know to fight in the future.
Advantages :- These vaccines are so much helpful because it introduce actual live pathogens into the body, it is an excellent simulation for the immune system. So live attenuated vaccines can result in lifelong immunity with just one or two doses.
Disadvantages :- Live attenuated vaccines are not given to people with weakened immune systems, such as people undergoing chemotherapy or HIV treatment, as there is a risk the pathogen could get stronger and cause sickness. Additionally, these vaccines must be refrigerated at all times so the weakened pathogen doesn't die. They can cause disease in some immunocompromised individuals .

gladiator answered 1 year ago

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