Question

A study of smoking status and the risk for recurrent coronary events after myocardial infarction (Rea et al, 2002) had the following results: a) 433 out of 2619 patients who survived to discharge had a recurrent coronary event within 3 years; b) With nonsmokers as the reference group, the relative risk for recurrent coronary events of persons who stopped smoking before their heart attack was 1.17 (95% CI, 0.93 to 1.43); for those who continued to smoke after their heart attack their relative risk of recurrent coronary events was 1.51 (95% CI, 1.10 to 2.07) c) For those who quit after their heart attack, their risk declined gradually over the three year follow up to that of nonsmokers. 11. In your own words, what do these findings mean for the population of patients who stopped smoking before their heart attack? confidence interval). 12. In your own words, what do these findings mean for the population of patients who continue to smoke after a heart attack?  

Answer 1

Purpose:
To assess the organization between smoking status and chance for recurrent coronary routine.

Design:
Retrospective, population-headquartered, inception cohort be trained.

Surroundings:
health upkeep organization from 1986 to 1996.

Patients:
2619 folks who survived to sanatorium discharge after a first myocardial infarction.

Measurements:
Relative chance (RR), assessed by way of utilizing Cox proportional-dangers regression analysis, for recurrent coronary movements in nonsmokers (persons without a historical past of smoking), former people who smoke (individuals who had stopped smoking before infarction), quitters (folks who stopped smoking after infarction), and active smokers (individuals who endured smoking after infarction).

Outcome:
on the time of incident infarction, 33.6% of patients had been nonsmokers, 35.5% have been former people who smoke, and 30.9% were lively smokers. Of the 808 individuals who had been lively smokers at the time of incident infarction, 449 quit smoking in the course of hospitalization or after discharge. With nonsmokers because the reference group, the multivariable RR for recurrent coronary events (n = 433) was 1.17 (ninety five% CI, zero.93 to 1.Forty three) for former people who smoke and 1.Fifty one (CI, 1.10 to 2.07) for active people who smoke. Amongst quitters, the RR reduced as period of cessation improved: With nonsmokers because the reference workforce, the RR for quitters used to be 1.Sixty two (CI, 1.02 to 2.Sixty one) if the period of cessation used to be zero to lower than 6 months, 1.60 (CI, 0.97 to 2.60) if the duration was 6 to less than 18 months, 1.Forty eight (CI, zero.Seventy six to 2.51) if the period was once 18 to lower than 36 months, and 1.02 (CI, 0.54 to 1.86) if the length was 36 months or more (P = zero.01 for trend).

Conclusion:
After incident myocardial infarction, smoking was associated with an expanded chance for recurrent coronary activities. In people who stop smoking after infarction, the chance declined to equal that of nonsmokers by 3 years after cessation.