Angina pectoris, myocardial infarction and chronic ischemic cardiopathy are clinical manifestations of coronary heart disease. Define...

Angina pectoris, myocardial infarction and chronic ischemic cardiopathy are clinical manifestations of coronary heart disease. Define the medical conditions above. Describe the histological changes observed in individuals with this disease.

Expert Solution

Angina pectoris:

A condition with chest pain radiating to shoulders,arms and neck due to inadequate blood supply to the heart.

Myocardial infarction:

A disease condition which is caused by the reduced or ceased blood supply to the coronary artery due to artherosclerosis and arterial occlusion by a thrombus or embolus.

Chronic ishemic cardiomyopathy:

A condition which is caused by the narrowing of the coronary arteries which supply blood to the heart and results in weakness of the haert muscle.

In patients with coronary artery disease,histopathologically atheromatous lesions are seen in the coronary arteries.In some patients,macrophages and lymphoplasmacyte-rich infiltrates are detected .The intimal and medial smooth muscle cells has swollen nuclei and abundant cytoplasm. In most of the patients, severe atheromatous lesions with chronic inflammatory cells infiltration and calcium deposits are observed in the tunica media and adventitia of coronary arteries .

Sydney Mullin answered 1 year ago

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