Discuss the different dosing considerations for pediatric patients compared to those for adults.

Expert Solution

Pediatric Patients:

Proper drug dosing depends on:

Age and weight: Young's rule, Clark's rule, Fried's rule
Overall health status
Condition of such biologic functions such as respiration and circulation
Stage of development of body systems for drug metabolism and drug elimination

In neonate, these biologic functions and systems are underdeveloped:

Renal function develops over the span of the first 2 yrs of life
So if the drug elimination rate is not properly considered then drug accumulation would occur leading to drug overdose and toxicity.

Dosing consideration for adult patients:

For the adults with normal health condition dosage is same but if they have health conditions like hepatic, renal, cardiac, cancer, etc. then special considerations of dosing is necessary.
Example: in chemotherapy, dosing is difficult as low dose will be ineffective whereas excessive causes toxicity.

Thus consideration of pediatric dosing is different from that of adults & it is necessary to avoid adverse drug events.

Nightingale answered 2 years ago

One general guideline for the maintenance dosing of heparin in pediatric patients is 100 units/kg every...

One general guideline for the maintenance dosing of heparin in pediatric patients is 100 units/kg every 4 hours, or 20,000 units/m2/24 hour administered continuously. The available injection for use by intravenous infusion contains 1000 USP Heparin Units/mL. For a 44-lb child, measuring 42 inches in height, calculate the difference between the quantities of heparin administered over a 24-hour period in (a) heparin units, (b) in milligrams of heparin (sodium), and (c) in milliliters of heparin injection.

In 250 words Describe considerations in dealing with pediatric patients and medication administration. In what ways...

In 250 words Describe considerations in dealing with pediatric patients and medication administration. In what ways are pediatric patients’ bodies different in terms of processing medications? How can you ensure safe medication administration for pediatric patients? What should you do if your dosage calculation is not considered safe according to the medication’s package insert

Compare the likely arrival rates of patients in a GP doctor’s surgery compared with those at...

Compare the likely arrival rates of patients in a GP doctor’s surgery compared with those at a hospital emergency department. What do you think would be the most appropriate assumptions for each of these in queuing models of each system? What are the likely characteristics of the service times in each of the two situations?

In 200 words Describe considerations in dealing with geriatric patients or older adults. What might some...

In 200 words Describe considerations in dealing with geriatric patients or older adults. What might some of the challenges be in communicating with them? How can you respond to these challenges? What are the physiologic considerations with older adults and how can they be addressed

Why is it important to obtain the height and weight of all patients, especially pediatric patients...

Why is it important to obtain the height and weight of all patients, especially pediatric patients and oncology patients, at each visit to the medical office?

Discuss the different types of drug administration and nursing considerations with the different administration methods.

Discuss how the reproductive rights of minors differ from those of adults.

Identify 5 different Pediatric Cardiovascular disorders and 5 different Pediatric Neurologic disorders . Include the appropriate...

Identify 5 different Pediatric Cardiovascular disorders and 5 different Pediatric Neurologic disorders . Include the appropriate Nursing Management for each disorder.

we will discuss the ethical considerations surrounding the forced containment of those who may become infected...

we will discuss the ethical considerations surrounding the forced containment of those who may become infected with the Ebola virus. you will first play the role of a senior advisor to the President of the United States. He has asked you to assist him in persuading the American people that containment is ethical. Provide the American people (i.e. class members) with your justifications for containment. You should persuade them to believe that containing their sick family members is ethical.

Dr. Grey wanted to see if doctors prescribed different treatments for OCD for male patients compared...

Dr. Grey wanted to see if doctors prescribed different treatments for OCD for male patients compared to females. Please use the following frequency tables for the data collected by Dr. Grey. SHOW ALL STEPS PLEASE Contingency table of Observed and Expected Frequencies of the different treatments (Drug vs. Cognitive Therapy) prescribed for patients with OCD. Therapy Totals Drug Cognitive Therapy Total Gender of Patient Observed Expected Observed Expected Man 20 10 30 Woman 15 15 30 Total 35 25 60...

Question