How do the amino acids aspartate and alanine provide a source of carbon for gluconeogenesis? Write...

How do the amino acids aspartate and alanine provide a source of carbon for gluconeogenesis? Write out the structures for the interconversions of these amino acids and their corresponding deaminated (amino group removed) α-keto acids.

Solutions

Expert Solution

These oxaloacetate and pyruvate are used in gluconeogenesis. This is the way by which alanine and aspartate participate in gluconeogenesis by getting converted in pyruvate and oxaloacetate respectively and giving their carbon to form glucose.

Phosphofructokinase is the rate limiting enzyme of gluconeogenesis. Gluconeogenesis is helpful when dietary supply of glucose is not available and the liver glycogen reserves are depleted, Glucose is synthesized from non carbohydrate sources. This is called gluconeogenesis.

gladiator answered 1 year ago

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