Question

A tRNA with the anticodon 5’ UAG 3’ can bind with how many of the following codons?

Group of answer choices

A. 0

B. 1

C. 2

D. 3

Answer 1

A three-base sequence (three nitrogen bases in a row) on mRNA is known as codon. It places a specific amino acid to the growing polypeptide. An anticodon is a three-base sequence on tRNA. It matches the codon.

The ribosomes attach to an mRNA sequence in protein building. The ribosome is made up of two parts that come together around the mRNA. During translation transfer RNA (tRNA) brings amino acids into the ribosome. The tRNA contains an amino acid and an anticodon use to pair up with the codon in the mRNA. Each nucleotide in RNA is made up of a sugar, phosphate, and one of these bases: adenine (A), uracil (U), cytosine (C), or guanine (G). Anticodons in tRNA pair up with mRNA codons with A pairing with U and C pairing with G. Codons are read in the 5' to 3' position, while anticodons are read from 3' to 5'. According to the wobble hypothesis proposed by Francis Crick. Crick found that the 3rd base was not very important for some codons because the bond was very weak in the 3rd base. According to these rules we need to orient the tRNA so we can pair it up with the mRNA answers. In this case, the tRNA is 3'-GAU-5', then complimentary pairs would be 5'-CUA-3' in the mRNA. This is the sequence for the first mRNA codon , however, the wobble hypothesis does apply to this group starting with CU and there are two other mRNA codons that start with CU.

so the correct answer is D.