Question

_{What role does the juxtaglomerular apparatus play in blood pressure regulation}

Answer 1

• Juxta glomerular apparatus consist of JG cells , which is smooth muscle modified on the afferent arteriole and macula densa ,which is a modified cells in distal convoluted tubule.
• Juxta glomerular apparatus play an important role in regulation of blood pressure.
• Macula densa sense the sodium conncentration .
• When arterial blood pressure falls below normal level , JG cells release a hormone called renin.
• Renin help to convert angiotensiogen from liver to angiotensin I.
• Angiotensin I is converted to angiotensin II by angiotensin converting enzyme.
• Angiotensin II is a powerful vasoconstricter , and increase blood pressure .
• Angiotensin II also act on adrenal gland to release aldosterone , which increase sodium reabsorption.