If a man has the premutation allele (on the X chromosome) for Fragile X syndrome, what...

If a man has the premutation allele (on the X chromosome) for Fragile X syndrome, what is the probability that he will pass it on to his son?

Expert Solution

Answer - The probability that he will pass on to his son is zero (0).

explanation -

As in the inheritance of sex chromosomes sons got a Y-chromosome from father and X-chromosoome from mother. Lets assume that the X-chromosome of father with permutation allele for fragile X-syndrome be represented by Xf while normal X chromosome be represnt as X.

The following cross may occur

Parent(P1) genotype Father, XfY X Mother, XX

Gamete genotype Xf Y X X

F1 offspring – Punnett square

Xf

Y

X

XfX

daughter

XY

Son

As shown with the punnett square, father always transmits its Y-chromosome to its son and as the permutation allele for fragile X-syndrome is located on X-chromosome. Thus, father can never inherit the the permutaion allele to his son.

Therefore, the probability that it will pass on to his son is zero (0).

gladiator answered 2 years ago

The Fragile-X syndrome is the most common inherited form of mental retardation in humans. The gene...

The Fragile-X syndrome is the most common inherited form of mental retardation in humans. The gene causing the disease has been cloned and shown to encode an RNA-binding protein that binds to a diverse yet specific pool of mRNA species in the brain. Based on what you know about RNA structure, do you think it likely that this protein binds to these RNA molecules using a similar mechanism that proteins use to bind DNA? Explain why or why not, and...

Hemophilia is a disease caused by a recessive allele on the X chromosome. Use a Punnett...

Hemophilia is a disease caused by a recessive allele on the X chromosome. Use a Punnett square to help describe the offspring phenotypes from the cross: heterozygous female crossed to male with hemophilia.

Fragile X syndrome is a sex-linked disease that leads to intellectual impairment in affected individuals. Explain...

Fragile X syndrome is a sex-linked disease that leads to intellectual impairment in affected individuals. Explain the mutation that leads to fragile X syndrome. How does the number of repeats affect gene expression?

A recessive allele on the X chromosome is responsible for red-green color blindness in humans. A...

A recessive allele on the X chromosome is responsible for red-green color blindness in humans. A woman with normal vision whose father is red-green color blind marries a male with normal vision. Which of the following best predicts the phenotypes of their children? A. All of the children will have normal vision. B. All of the daughters will have normal vision, and half of the sons will be red-green color blind. C. All of the daughters will have normal vision,...

The allele frequency for the spider syndrome allele in a flock of sheep is 0.41. The...

The allele frequency for the spider syndrome allele in a flock of sheep is 0.41. The normal allele N is dominant to the n allele, and homozygous nn lambs do not survive to reproduce. In the flock, all NN and Nn animals are retained, and all nn animals are removed from the herd. Determine the allele and genotypic frequencies in the flock following a single generation of selection.

8. A gene for sweat gland production is found on the X chromosome. If a man...

8. A gene for sweat gland production is found on the X chromosome. If a man who lacks sweat glands marries a woman who has normal sweat glands, what will be the phenotype of their children? A. All of the boys will lack sweat glands. B. All of the girls will lack sweat glands. C. The girls will have sweat glands in some areas, but lack sweat glands in others. D. All of the boys will have sweat glands. E....

Question

If a man has the premutation allele (on the X chromosome) for Fragile X syndrome, what...

Solutions

Expert Solution

Related Solutions

The Fragile-X syndrome is the most common inherited form of mental retardation in humans. The gene...

Hemophilia is a disease caused by a recessive allele on the X chromosome. Use a Punnett...

Fragile X syndrome is a sex-linked disease that leads to intellectual impairment in affected individuals. Explain...

A recessive allele on the X chromosome is responsible for red-green color blindness in humans. A...

The allele frequency for the spider syndrome allele in a flock of sheep is 0.41. The...

8. A gene for sweat gland production is found on the X chromosome. If a man...

Explain what occurs on chromosome 15 in a patient with Angelman syndrome that DOES NOT have...

Human fragile sites are associated with _____. chromosome breakage replication late in S phase stalling of...

Bio 101 Mitosis Lab What are the definitions of the following terms: DNA: Chromosome: Gene: Allele:...

What is the inactivation of the X chromosome? What is a Barr body?