Question

Neutraceuticals are of research interest both as preventative factors and as sources of potential new treatments for several chronic inflammatory conditions. With the exception of flavanoids discuss some of the potential new neutraceuticals currently under investigation and the mechanisms by which they may aid in alleviating chronic inflammatory disease.

Answer 1

First of all, a nutraceutical is a pharmaceutical alternative which claims physiological benefits. Nutraceuticals are also used to improve health, it delay the aging process, prevent chronic diseases, increase life expectancy, or support the structure or function of the body. Nutraceutical antioxidants such as curcumin, lutein, lycopene, turmerin and β-carotene may exert positive effects on specific diseases such as Alzheimer's disease by combating the oxidative stress. When it comes to cardiovascular diseases, Phytosterols compete with dietary cholesterol by blocking the uptake as well as facilitating its excretion from the body ;Buckwheat seeds possess phytosterols, flavonoids, flavones, proteins and thiamin-binding proteins, etc., Buckwheat proteins lower blood cholesterol and hypertension. In case of diabetics, Omega-3 fatty acids have been suggested to reduce glucose tolerance in patients predisposed to diabetes and Lipoic acid is an antioxidant which is used for the treatment of diabetic neuropathy and seems to be effective as a long-term dietary supplement for protection of diabetics from complications.
Many evidences indicate that the mechanism of natural compounds involve a wide angle of biological processes including activation of antioxidant defenses, signal transduction pathways, cell survival-associated gene expression, cell proliferation and differentiation.