Question

In: Nursing

Age: 63 years Weight: 85 Kg   Diagnosis: HTN Gender: female Rx Hydralazine 50 mg, bid, hs...

Age: 63 years

Weight: 85 Kg  

Diagnosis: HTN

Gender: female

Rx

Hydralazine 50 mg, bid, hs

Fluvastatin 80 mg, one tab od

Spironolactone tab 25 mg, 1/2 tab bid

Amitriptyline 25 mg, od

all medication for 3 months

Note: patient has sever muscle pain with fever, what is your advice?

discuss this prescription and why give the patient this medication and what the recommendation for the patient?

Solutions

Expert Solution

Hydralazine, 50 mg to be taken twice a day, is a Vasodilator, which reduce blood pressure by dilatation of blood vessels, is used with or without other medications to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Hydralazine is called a vasodilator. It works by relaxing blood vessels so blood can flow through the body more easily.

Fluvastatin, 80 mg once a day, is used along with a proper diet to help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood. It belongs to a group of drugs known as "statins." It works by reducing the amount of cholesterol made by the liver. Lowering "bad" cholesterol and triglycerides and raising "good" cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks.

Spironolactone, 25 mg, half tab twice a day, is known as a "water pill" (potassium-sparing diuretic).Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling (edema) caused by certain conditions (such as heart failure, liver disease) by removing excess fluid and improving symptoms such as breathing problems.

Amitriptaline, 25 mg once a day, is used to treat mental/mood problems such as depression. It may help improve mood and feelings of well-being, relieve anxiety and tension, help sleep better, and increase energy level. This medication belongs to a class of medications called tricyclic antidepressants. It works by affecting the balance of certain natural chemicals (neurotransmitters such as serotonin) in the brain.

These are the medications given for a patient with hypertension.

Some of the side effects caused due to Hydralazine, an anti hypertensive drug is severe tiredness, aching/swollen joints, rash on nose and cheeks, swollen glands, signs of kidney problems (such as change in the amount of urine, bloody/pink urine), signs of infection (such as fever, chills, persistent sore throat), easy bruising/bleeding. Some of the other serious side effects will be serious side effects, including: chest/jaw/left arm pain.

Hence the client with muscle pain and fever could be the side effects of the medications Vasodilators like Hydralazine. Inform the doctor for any symptoms of arthritis, fever, tiredness

For people with high blood pressure, some types of nonsteroidal anti-inflammatory drugs (NSAIDs) can be risky. Some of these NSAIDs reduce the blood flow to the kidneys. The kidneys -- which filter blood -- work more slowly, and so fluid builds up in the body. The increased fluid drives up blood pressure.

Other pain relievers may be less dangerous. Aspirin is also an NSAID, but experts think that it's safer for people with hypertension. Acetaminophen -- the active ingredient in Tylenol -- is a different type of painkiller that doesn't raise blood pressure as a side effect.

Advise for patient with hypertensives are:

  • Be familiar with the name and dosage of the drugs you are taking. Be cautious about their possible side effects
  • Take the drugs regularly as instructed by the doctor in order to have effective control of hypertension. Keep taking the same dosage of drugs even if the conditions improve unless the doctor has suggested to change the antihypertensive regime.
  • Take medicines at the same fixed time every day as far as possible. If a dose is missed, take it as soon as possible unless it is almost time for the next scheduled dose. In that case, skip the missed dose and take the next dose as directed. Do not take double doses
  • The drugs should not be taken with alcoholic drinks to avoid dizziness or fainting
  • If feel light-headed or dizzy, one should not drive or operate machinery and seek doctor’s advice if the symptom persists.
  • Make sure there is sufficient drug stocks for several days. Do not wait till the last minute to refill the prescription.

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