After viewing the film WIT identify two pivotal moments which struck you as opportunities for better psychosocial care. Describe these moments, your initial reaction, and what you would do differently if you were the care provider. Think of this opportunity as a way to reflect on your practice and how we can all do better.

Duality of Human Nature. Examine the characters in “The Lottery” as they relate to this theme. Which characters show two sides of humanity? Which characters are seemingly good natured; however, they show a different side during the events of the lottery. Make sure you have three different characters or three different moments where a character(s) show two sides.

The enzyme enolase catalyzes the following reaction in the glycolysis pathway (Chapter 14):

2-phosphoglycerate ® phosphoenolpyruvate + H₂O

Dehydration of 2-phosphoglycerate (2PG) results in phosphoenolpyruvate (PEP), which is a high-energy phosphate donor that can be used to phosphorylate ADP to make ATP. Thus, this is an important reaction to set up the final step of the pathway.

Balantidiasis is a disease caused by the ciliated protozoan, Balantidium coli. As it is a eukaryote, antibiotics against bacteria will not affect it. Your research group has recently found that members of the Balantidium genus possess an unusual form of enolase, which may allow you to develop an inhibitor that would affect it (and not the enolase in human cells). You have cloned the gene for the enolase from Balantidium coli, and expressed it in E. coli (which is a bacterium) and then purified the enzyme. You call this BcEno, to distinguish it from the other types of enolase. The polypeptide is predicted to be 32 kDa in size, and protein behaves as a homodimer with 2 active sites in each dimer. It requires Mg²⁺ for activity and is inhibited by EDTA, a chelator of divalent cations.

1. You perform a kinetic analysis on the enzyme by measuring the rate of catalysis in the presence of increasing amounts of 2PG. You initiate each reaction by adding 5 µL of a solution of 0.1 µg/mL enzyme to each assay tube, which already contains buffer and various amounts of 2PG in a total volume of 95 µL. After each reaction has proceeded for 30 seconds, during which time it should still be in the initial phase, you terminate it by adding 10 µL of 1 M EDTA. You then quantify the amount of PEP.

From these data, calculate k_cat and K_m of BcENO for 2PG:

k_cat =

K_m =

What is its specificity constant for 2PG?

Comment on the efficiency of this enzyme – is it “catalytically perfect”

2. The most promising molecule produced by your synthesis team is code-named BCEI-17. You repeat the assays exactly as in part (a), except that the tubes also contain BCEI-17. Here is the relevant data:

What sort of inhibitor is BCEI-17: competitive, uncompetitive, or mixed?

What is the K_I and/or K_I' of BCEI-17?  

Do you believe that the process of alteration in human/animal cells falls under the ethics of beneficence? Why or why not?

A 36 year old first-time mother develops complications during labor and requires an emergency cesarean section. How does postpartum nursing care differ for this mother? What assessment and monitoring should the nurse perform?

This is a 35-year-old HIV-positive male with progressive lymphadenopathy and unexplained fever, night sweats, and chills. Low osmolar CT scan of the chest, abdomen, pelvis, and neck showed extensive lymphadenopathy involving mediastlnum and left hilum, paratracheal nodal chains, retroperiteoneum, right iliac nodal chains, and right inguinal nodes. There were several areas of atelectasis evident in the lung. CT guided needle biopsy of an emerged mediastinal node that was suspicious for tuberculosis. This was accomplished using visipaque contrast. The node in fact was AFB-positive. The patient was placed on respiratory isolation and serial sputums were obtained. The patient’s sputum contained positive AFB on concentrated specimen. Also, during the hospitalization, the patient complained of swelling in the bilateral lower extremities. Dopplers were negative for DVT. The patient was diagnosed with tuberculosis of intrathoracic, retroperitoneum, and Inguinal lymph nodes, tubercle bacilli found by microscopy. The patient will be referred to the clinic for management of his HlV disease and associated tuberculosis. What codes are assigned?

Need help with ICD-10-CM Code with POA indicator and MS'DRG and lCD-10-PCS Code.

1) Compare and contrast the 3 study approaches (Qualitative, Case-control, and Cohort) including advantages and disadvantages.

1. Describe the positive symptoms of schizophrenia and relate those symptoms to the case study patient.  

2. Explain the genetics of schizophrenia.

3. The APRN reviews recent literature and reads that neurotransmitters are involved in the development of schizophrenia. What roles do neurotransmitters play in the development of schizophrenia?

4. The APRN reviews recent literature and reads that structural problems in the brain may be involved in the development of schizophrenia. Explain what structural abnormalities are seen in people with schizophrenia.

5. Discuss the role genetics plays in the development of bipolar 2 disorders.  

6. Explain how the hypothalamic-pituitary-adrenal (HPA) system may be associated with bipolar type 2 disease.

7. Discuss the role inflammatory cytokines play in the development and exacerbation of bipolar type 2 symptoms

8. Discuss the role of the amygdala in bipolar disorder.

9. How does neurochemical dysregulation contribute to bipolar disorders?

10. What is the current status of the use of nutraceuticals in management of depression?

11. What are panicogens and how do they contribute to the development of panic attack symptoms?

12. How does the GABA-benzodiazepine (BZ) receptor systems contribute to panic attacks/disorders?

13. Describe the areas of the brain that are associated with social anxiety disorder.

14. How is oxytocin associated with anxiety disorder (SAD)?

15. Discuss the role of neurotransmitters in the expression of generalized anxiety disorder (GAD).  

16. Explain the structural brain changes that occur in people with GAD.

17. Describe the changes seen in the brain structure in patients with PTSD.

18. Briefly discuss the role glucocorticoids may have on the development of PTSD.

19. What is primary pathophysiology of obsessive-compulsive disorder (OCD?

20. Describe the role the dorsal anterior cingulate cortex (dACC) has in reinforcement of obsessive behaviors.

Imagine that you are a public health nurse, and you and your colleagues have determined that the threat of a deadly new strain of influenza indicates a need for a mass inoculation program in your community.

0What public health data would have been used to determine the need for such a program? Where would you locate public health data? What data will be collected to determine the success of such a program? How might you communicate this to other communities or internationally?

A 23-year-old male with Type 1 diabetes presents to the ER complaining of fatigue and malaise. He tells you he has skipped his insulin injections the previous two days. His labs are:

The RN to BSN program at Grand Canyon University meets the requirements for clinical competencies as defined by the Commission on Collegiate Nursing Education (CCNE) and the American Association of Colleges of Nursing (AACN), using nontraditional experiences for practicing nurses. These experiences come in the form of direct and indirect care experiences in which licensed nursing students engage in learning within the context of their hospital organization, specific care discipline, and local communities.

Note: The teaching plan proposal developed in this assignment will be used to develop your Community Teaching Plan: Community Presentation due in Topic 5. You are strongly encouraged to begin working on your presentation once you have received and submitted this proposal.

Select one of the following as the focus for the teaching plan:

1. Primary Prevention/Health Promotion
2. Secondary Prevention/Screenings for a Vulnerable Population
3. Bioterrorism/Disaster
4. Environmental Issues

Use the "Community Teaching Work Plan Proposal" resource to complete this assignment. This will help you organize your plan and create an outline for the written assignment.

1. After completing the teaching proposal, review the teaching plan proposal with a community health and public health provider in your local community.
2. Request feedback (strengths and opportunities for improvement) from the provider.
3. Complete the "Community Teaching Experience" form with the provider. You will submit this form in Topic 5.

Prepare this assignment according to the guidelines found in the APA Style Guide, located in the Student Success Center. An abstract is not required.

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.

A 22-year-old woman comes to the office due to worsening cough. The patient has been coughing every day for the past several months, but over the last 4 weeks, the cough has worsened, with increased amounts of thick sputum and shortness of breath. Streaks of blood have been present in the sputum on several occasions. The patient also has a history of chronic sinusitis and repeated hospitalizations for airway infections. She takes pancreatic enzyme supplements for chronic diarrhea. She does not use tobacco, alcohol, or illicit drugs. Physical examination reveals nasal polyps, a barrel-shaped chest, bilateral coarse lung crackles, and digital clubbing. Chest x-ray shows hyperinflated lungs and dilated, thickened airways. The patient is diagnosed with cystic fibrosis.

Sputum culture from this patient is most likely to yield which of the following organisms?

Pseudomonas aeruginosa

Yersinia pestis

Yersinia enterocolitica

Bartonella henselae

Streptococcus pneumoniae

Staphylococcus aureus