Question

4. how do crebs cycle and glycolysis communicate?

a. who is the molecule in crebs cycle that influences the glycolysis pathway?

b. who is the enzyme that is relevant to that in crebs cycle?

c. to which enzyme in glycolysis pathway will the molecule in question a attach?

d. how does this bond affect the activity of the enzyme from b in glycolysis pathway?

Answer 1

Please find the answers below:

Answer a:The glycolysis is the primary metabolic cycle that operates in the cytosol whereas the Kreb's cycle operates in the mitochondria. They are connected by the activity of enzyme pyruvate dehydrogen complex which recruits the entry of acetyl coenzyme A into Kreb's cycle from pyruvate.

Answer b: As suggested, the enzyme pyruvate dehydrogenase is relevant to that in Kreb's cycle.

Answer c: The enzyme reacts with pyruvate (generated from glycolysis) and generates acetyl coenzyme A.

Answer d: Since the product of glycolysis represents to the the substrate of enzyme pyruvate dehydrogenase, the activity of this enzyme thus depends with a positive correlation between the presence of substrate, thus, optimum activity of glycolysis and aerobic respiration. More is glycolysis taking place, more pyruvate it generates thus providing substrate for biological activity of pyruvate dehydrogenase.