In: Biology
how many atp are consumed by the glycolysis of a single molecule of glucose
in the first half glycolysis that is energy-consuming phase need 2 ATP
The first step in glycolysis is catalyzed by enzyme hexokinase, Hexokinase phosphorylates glucose using ATP as the source of the phosphate also called the activation by po4-, producing glucose-6-phosphate, a more reactive form of glucose. then the enzyme isomerase converts glucose-6-phosphate into one of its isomers, fructose-6-phosphate by changing the position of groups in the structure. An enzyme that catalyzes the conversion of a molecule into one of its isomers is an isomerase. The third step is the phosphorylation of fructose-6-phosphate, catalyzed by the enzyme phosphofructokinase. A second ATP molecule donates a high-energy phosphate to fructose-6-phosphate, producing fructose-1,6-bisphosphate. phosphofructokinase is a rate-limiting enzyme. It is active when the concentration of ADP is high; it is less active when ADP levels are low and the concentration of ATP is high. The newly-added high-energy phosphates further destabilize fructose-1,6-bisphosphate. The fourth step in glycolysis employs an enzyme, aldolase, to cleave 1,6-bisphosphate into two three-carbon isomers: dihydroxyacetone-phosphate and glyceraldehyde-3-phosphate.In the fifth step, an isomerase transforms the dihydroxyacetone-phosphate into its isomer, glyceraldehyde-3-phosphate.