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LAC operon undergoes both negative and positive control of transcription initiation. Look over the structure of...

LAC operon undergoes both negative and positive control of transcription initiation. Look over the structure of the Lac operon and its regulatory gene (LAC I).

a. Describe the negative control of this inducible operon. How does it prevent transcription initiation?

b. Describe the positive control of LAC operon. Include in your discussion, the CAP protein, adenlyl cyclase, and cAMP protein. How does it increase transcription to a higher rate?

c. In presence of glucose, inducer exclusion (keeping lactose out of the cell) is an important means of controlling transcription of the LAC operon. Phosphotranferase systems (PTS) of transporting sugars are essential to keeping the lactose transporter inactive until glucose is no longer available in the medium. Describe how the PTS is involved in both activating the lactose transporter and adenylyl cyclase in the absence of glucose?

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gladiator answered 3 hours ago
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