Question

What do I know about these medications?

What is the recommended dose, the route and the best time of the day to take it

what lab results I need regarding each medication?

what are the approved use of each medication?

what are the most common diseases treated by the listed medications?

Are any off-label uses approved for each drug?

For these medications please answer the one above :)

Isosorbide

Potassium chloride

Answer 1

Isosorbide mononitrate:- it is used to prevent chest pain (angina) in patients with a certain heart condition ( coronary artery disease). This medication belongs to a class of drugs know as nitrates.

Isosorbide dinitrate :- it is used to treat or prevent attacks of chest pain. Only the sublingual tablet should be used to treat an angina attack that has already begun . Isosorbide dinitrate regular and extended- release tablets are used to prevent angina attacks but will not treat an angina attack.

Pottasium chloride :- it is used to prevent or to treat low blood levels of pottasium(hypokalemia). Pottasium levels can be low as a result of a disease or from taking certain medicines, or after a prolonged illness with diarrhea or vomiting.

For pottasium chloride - serum pottasium level to be monitored.

Isosorbide- liver function and renal function

Approved use of isosorbide - vasodilator- angina pectoris

Pottasium chloride- maintaining electrolyte balance- hypokalemia.

Recommended dosage isosorbide- immediate release 5- 10mg PO twice daily initially( 5 mg in small patients). 7 hr hr apart; increased to 10 mg PO q 12 he by day 2 or 3 ; maintenance: 20 mg PO q 12 hr . Extended release : 30-60 mg PO once daily Inthe morning initially; may be increased to 120 mg PO once daily wait atleast 3 days between increase.

Take on empty stomach 30 min before or 1 hr after meal.

Extended - release tablet should be swallowed whole .must not be chewed crushed or split.

Pottasium chloride- hypokalemia - 20-40mEq BID - QID

Hypokalemia prophylaxis - start 20 mEq PO qDay

Dosage varies adjust to serum pottasium levels.

Achlasia Cardia - off label uses approved for isosorbide