Question

automated DNA extraction technique/equipment explain it in detail.

Answer 1

DNA isolation of purification of DNA from sample using a combination of physical and chemical methods. The first isolation of DNA was done in 1869 by Friedrich Miescher , currently it is routine procedure in molecular biology or forensic analyses . For the chemical method , there are many different kits used for extraction , and selecting the correct one will save time on kit optimization and extraction procedures . PCR sensitivity detection is considered to show the variation between the commercial kits. Robotic liquid handling technology in automated DNA extraction systems can streamline the tasks involved in extracting DNA from a sample , such as serial dilution and cherry picking . Systems typically also include functions such as shaking ,

temperature control , and PCR protocols. DNA extraction is used in many types of biological research including molecular biology , forensics , pathology , environmental research , and drug discovery . Features to look for in choosing an automated DNA extraction system include integration with laboratory information management system , full start - to - finish automation , error control , and safeguards against contamination. Automation in DNA isolation is a necessity for routine practice employing molecular diagnosis of infectious agents . to this end , the development of automated systems for the molecular diagnosis of microorganisms directly in blood samples is at its beginning . important characteristics of systems demanded for routine use include high recovery of microbial DNA , DNA - free containment for the reduction of DNA contamination from exogenous sources, DNA- free reagents and consumables, ideally a walkaway system, and economical pricing of the equipment and consumables .

The Qiagen BioRobot EZ1 is small ,rapid and reliable automated DNA extraction instrument capable of extracting DNA from up to six samples in as few as 20 min using magnetic bead technology.