List 3 different types of cis-acting elements that influence eukaryotic gene expression and briefly describe their function.

Expert Solution

Cis-acting elements:
1. TATA box -
* binding site for TATA binding protein and associated factors.
* It is a core promoter - plays crucial role in basal level gene expression.

2. GC box and CAAT box :
* Those are promoter proximal elements.
* helps in compelete level of expression
* Binding sites for transcription factors.

3. Enhancers :
* short sequence elements, some similar to promoter sequences.
* required for maximal transcription of a gene.
* can be upstream or downstream of the transcription initiation site
* modulate from a distance of thousands of base pairs away from the initiation site.
* Activators bind these sequences and other protein complexes form, postulated to bring the enhancer complex close to the promoter and increasing transcription.

gladiator answered 2 years ago

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