Question

Describe the stages of the inflammatory response

Answer 1

Stages of Inflammatory Response:

Inflammation is the damage of body tissue as a result of injury due to trauma. The inflammatory response is the body's normal defenses to overcome the infection that exists in the body where the infectious agent is growing and multiplying in the tissues. The stages that take place in the sequence of the inflammatory process

1. microcirculation
2. vasodilation
3. increased vascular permeability
4. leukocytic cellular infiltration.

Immediately after injury, the vasoconstriction occurs followed by vasodilation which results in increased blood flow through the microcirculation. This develops heat and redness. then, increased vascular permeability occurs and plasma protein leak into the inflamed tissues causes swelling. Due to the pressure of fluids on the nerve endings, pain and irritation occur as a result of chemical mediators(Bradykinin) released on the site. Loss of function occurs as a result of pain and swelling.

Once the fluid leaks into the surrounding tissues, the red blood cells, white blood cells, and platelets remain in the blood, become more viscous. Then the process of phagocytosis occurs when the white blood cells moved to the injury site and engulf the organisms and remove the cellular debris. The clot formation occurs due to fibrinogen present in the plasma fluid which prevents further spread of infection.