In: Nursing
Two current nursing journals with evidenced-based practice must be used to support the findings on CYSTIC FIBROSIS.
In Recent days nursing journals with evidence based practice have been used to get findings on Cystic fibrosis.
The journal is devoted to promoting the research and treatment of cystic fibrosis. To this end the journal publishes original scientific articles, editorials, case reports, short communications and other information relevant to cystic fibrosis.
Cystic fibrosis (CF) is a genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine.Long-term issues include difficulty breathing and coughing up mucus as a result of frequent lung infections. Other signs and symptoms may include sinus infections, poor growth, fatty stool, clubbing of the fingers and toes, and infertility in most males.Different people may have different degrees of symptoms.
Symptoms
The main signs and symptoms of cystic fibrosis are salty-tasting skin,poor growth and poor weight gain despite normal food intake,accumulation of thick, sticky mucus,frequent chest infections, and coughing or shortness of breath.Males can be infertile due to congenital absence of the vas deferens. Symptoms often appear in infancy and childhood, such as bowel obstruction due to meconium ileus in newborn babies.
Pathophysiology
Most of the damage in CF is due to blockage of the narrow passages of affected organs with thickened secretions. These blockages lead to remodeling and infection in the lung, damage by accumulated digestive enzymes in the pancreas, blockage of the intestines by thick feces, etc. Several theories have been posited on how the defects in the protein and cellular function cause the clinical effects. The most current theory suggests that defective ion transport leads to dehydration in the airway epithelia, thickening mucus. In airway epithelial cells, the cilia exist in between the cell's apical surface and mucus in a layer known as airway surface liquid (ASL).
Treatment
There is no cure for cystic fibrosis, but treatment can ease symptoms, reduce complications and improve quality of life.
Options for certain conditions caused by cystic fibrosis include:
Nasal and sinus surgery. ...
Oxygen therapy. ...
Noninvasive ventilation. ...
Feeding tube. ...
Bowel surgery. ...
Lung transplant.