Lithium Overdose can be treated with which of the following,

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Expert Solution

Lithium toxicity typically occurs as three forms acute overdose in a person who does not normally take the drug, acute-on-chronic, or chronic. The toxicity resulting from chronic use and accumulation of lithium is more severe.

Activated charcoal:

It binds very poorly to lithium, it’s the use of activated charcoal should be cautiously used for patients who are suspected of ingesting other chemicals, due to the poor binding ability to lithium.

Gastric lavage:

Can be used for very recent ingestion.

Whole bowel irrigation:

In case of ingestion of large amounts or use of sustained release product.

Sodium polystyrene sulfonate (Kayexelate):

Some studies suggest that Kayexelate binds to ingested lithium

Intravenous fluid therapy :

Fluid replacement with isotonic saline boluses, followed by an infusion to maintain an effective urine output.

Hemodialysis or Peritoneal dialysis:

It is the best and effective method for removal of lithium from the body.Repeated hemodialysis sessions are commonly used.

Continuous renal replacement therapy (CRRT, also known as continuous venovenous hemofiltration or CVVH) :

Used in place of hemodialysis in many settings.

Nightingale answered 2 years ago

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