Question

Discuss the symptoms for which PPIs are prescribed and the intended target of these drugs. Next, address an organelle that would also be affected by these drugs. Based on the function of that organelle, do the issues in the website make biological sense? Lastly, propose an alternative approach for a patient with these symptoms that would not require him or her to remain on PPIs long-term. Does your approach address the source of their symptoms?

Answer 1

Proton pump inhibitors (PPIs) are the most commonly prescribed class of medication for the treatment of heartburn and acid-related disorders. They work by blocking the site of acid production in the parietal cell of the stomach.T
According to me getting off your proton pump inhibitor
1)People with gastroesophageal reflux disease (GERD), or indigestion, can consider tapering off their PPI after having no symptoms for a minimum of three months.
2)Folks taking PPIs for treatment of stomach or duodenal ulcers for four to eight weeks do not require tapering down, and you can attempt to just stop them.
3)Don’t forget that relapse symptoms may occur. When you discontinue PPIs, there is rebound gastric hyper-secretion in those who have been on them for prolonged periods of time. Rebound symptoms should resolve within two weeks.
4)Folks who have been taking PPIs for a period of six months might consider tapering down their dose instead of stopping cold turkey. However, you might be wondering how to properly taper down. Try to reduce your dose by 50% every week. Once you are on the lowest dose for one full week, you can try stopping your PPI.