Question

In: Biology

Explain how the type of disease, Thalassemia affects the skeletal system. Is the disorder systemic or...

Explain how the type of disease, Thalassemia affects the skeletal system. Is the disorder systemic or focal and how does this affect it’s manifestation on or in the bones.

Solutions

Expert Solution

Thalassemia is a genetic blood disorder.It is a systemic disorder.The pathogenesis for this disorder is due to defect in globin chain of hemoglobin.Hemoglobin normaly consist of 4 globin chain 2 alpha and 2 beta chains ,its decreased synthesis or absence cause the disease.Beta thalassaemia is most commonly found.Based on the number of chains affected it can be major or minor thalassaemia,based on homozygosity either homozygous (major) or heterozygous(minor)

Thalassaemia pathogenesis eg given beta thalassaemia

Severe reduction in beta chain synthesis

gladiator answered 4 months ago
Next > < Previous

Related Solutions

A complex, multi-system disease process is defined as a condition or disorder that either affects the...
A complex, multi-system disease process is defined as a condition or disorder that either affects the whole body or involves multiple organs. Your textbook uses diabetes as an example of a complex, multi-system disease process; while fundamentally a disease of dysfunctional glucose regulation, it affects nearly every system in the body and leads to altered elimination, altered perfusion, and so on. You may select any complex, multi-system disease process that interests you except diabetes--the text has covered this disease in...
SYSTEMIC LUPUS IS A DISORDER THAT AFFECTS CONNECTIVE TISSUE THROUGHOUT THE BODY.Explain why the symptoms and...
SYSTEMIC LUPUS IS A DISORDER THAT AFFECTS CONNECTIVE TISSUE THROUGHOUT THE BODY.Explain why the symptoms and complications associated with Lupus can be so variable in different patients, and discuss some of the common symptoms of lupus and how those symptoms relate to damage to the connective tissue?
Parkinson’s disease is a motor disorder that generally affects people in their later years a) Why...
Parkinson’s disease is a motor disorder that generally affects people in their later years a) Why do the motor symptoms occur? b) Discuss the treatments for Parkinson’s disease For each treatment, explain the pharmacological mechanism of action, and Explain what this is doing to the body’s dopaminergic system.
Explain how multiple sclerosis affects the nervous system ?
Explain how multiple sclerosis affects the nervous system ?
explain eating disorder area of concern such as disease state, metabolism, treatment in a disease.
explain eating disorder area of concern such as disease state, metabolism, treatment in a disease.
Psychology Chapter 8: Let's talk movement Parkinson’s disease is a progressive disorder that affects the dopamine-containing...
Psychology Chapter 8: Let's talk movement Parkinson’s disease is a progressive disorder that affects the dopamine-containing neurons in the substania nigra that control muscle movement. People with Parkinson’s experience trembling, muscle rigidity, difficulty walking and problems with balance. Parkinson’s disease usually develops after age 50 but a small number of younger people are also affected. Parkinson’s Disease and Aging The loss of dopamine containing cells in Parkinson’s disease is actually an extreme form of the natural loss of dopamine cells...
Explain what an endocrine disorder is and what affects it may have on the body. Are...
Explain what an endocrine disorder is and what affects it may have on the body. Are they the same as autoimmune disorders? Compare and Contrast Cushing’s disease and Addison’s disease (make sure to include: the gland and hormone involved/causes, characteristics/symptoms, treatment) Differentiate between hypothyroidism, hyperthyroidism, cretinism, and myxedema. (do not just write their definitions.) Back in the day, surgeons would perform a thyroidectomy on patients with thyroid disorders. When they removed the full thyroid gland, their patients would develop neuromuscular...
Lupus is a systemic autoimmune disease that occurs when the body's immune system attacks its own...
Lupus is a systemic autoimmune disease that occurs when the body's immune system attacks its own tissues and organs. Inflammation caused by Lupus can affect many different body systems | including joints, skin, kidneys, blood cells, brain, heart, and lungs. Lupus can be difficult to diagnose. (a) One issue with diagnosing Lupus is that the intensity of the inflammation is determined as much by the triggering factors as by the patient itself. Which challenge in object recognition would map to...
The type of product a company produces affects the type of accounting system needed to determine...
The type of product a company produces affects the type of accounting system needed to determine product cost. The 2 most common types of costing systems are job-order costing and process costing. Respond to the following in a minimum of 175 words: Compare and contrast job-order and process costing systems. How can events in a job-order costing system affect financial statements? How can events in a process costing system affect financial statements? Provide specific examples for each type.
The type of product a company produces affects the type of accounting system needed to determine...
The type of product a company produces affects the type of accounting system needed to determine product cost. The 2 most common types of costing systems are job-order costing and process costing. Respond to the following in a minimum of 175 words: Compare and contrast job-order and process costing systems. How can events in a job-order costing system affect financial statements? How can events in a process costing system affect financial statements? Provide specific examples for each type.
ADVERTISEMENT
Subjects
ADVERTISEMENT
Latest Questions
ADVERTISEMENT