Question

What are the causes of type 2 diabetes?

What is the relationship between insulin resistance and hyperinsulinemia?

What are endocrine disrupters and what are their functions in our body? Provide some examples.

How does concentration of glucose effect insulin secretion?

Answer 1

The causes of type 2 diabetes include the genetic predisposition, lifestyles such as inactivity and environmental factors, such as excess weight are the most important ones. The body may become resistant to insulin or the pancreas may stop producing enough insulin.

Insulin resistance; a condition in which our body doesn't respond well to the effects of insulin leads to more and more secretion of insulin i.e. Hyperinsulinemia to compensate for decreased action.

The naturally occurring compounds or man-made substances mimicking or interfering with the function of hormones in the body Endocrine disruptors are called; endocrine disruptor’s example is diethylstilbestrol (DES), a synthetic estrogen.

The concentration of glucose effects insulin secretion as insulin is secreted in response to high glucose levels and it leads to the transport of glucose and hence in lowering the concentration of glucose in the blood.