The renin-angiotensin system (RAS) is a signalling pathway that
acts as a homeostatic regulator of vascular function. Its systemic
actions include the regulation of blood pressure, natriuresis, and
blood volume control. ACE2 is a type 1 integral membrane
glycoprotein, that is expressed and active in most tissues. The
highest expression of ACE2 is observed in the kidney, the
endothelium, the lungs, and in the heart. ACE2 is the
angiotensin-converting enzyme II.
It has been reported that ACE2 is the main...