Investigate the pathway of how this volatile fatty acid contributes to gluconeogenesis. Make a diagram/flowchart with...

Investigate the pathway of how this volatile fatty acid contributes to gluconeogenesis. Make a diagram/flowchart with the key steps in this pathway, including the formation of methylmalonyl-CoA.

Expert Solution

Propionic acid is a volatile fatty acid. It is converted to succinyl-CoA via methylmalonyl-CoA as an intermediate. This succinyl-CoA enters TCA cycle to generate oxaloacetate which is a precursor for gluconeogenesis. Oxaloacetate is converted to phosphoenol pyruvate (PEP) by PEP carboxy kinase (PEPCK). This PEP is then converted into glucose via gluconeogenesis.

Oxaloacetate can also be formed from pyruvate via pyruvate carboxylase.

Malate can also converted into pyruvate via malic enzyme.

gladiator answered 1 year ago

Draw a diagram of gluconeogenesis pathway. Number of each step in the diagram, include the structure...

Draw a diagram of gluconeogenesis pathway. Number of each step in the diagram, include the structure of each intermediate, names of enzymes involved (in the table below), the names of each consumed or produced product and the full name of each intermediate.

Gluconeogenesis 1. As part of the metabolic pathway for amino acid degradation, malate not oxalacetate is...

Gluconeogenesis 1. As part of the metabolic pathway for amino acid degradation, malate not oxalacetate is transported into the cytoplasm form the mitochondrion. Why malate? 2. Explain how carbon dioxide serves to couple ATP hydrolysis into the energetics of the synthesis of PEP to pyruvate? Provide both mechanism and energetics. These two questions are from a study guide and I'm struggling finding the answers in my notes and text book, thank you for your help!

Glycolysis (and its sister pathway gluconeogenesis) and the citric acid cycle are often referred to as...

Glycolysis (and its sister pathway gluconeogenesis) and the citric acid cycle are often referred to as the Central metabolic Pathways. Identify at least 3 other metabolic in aerobic organisms (animal and or plant) that interact with these two central pathways. Briefly describe the connections and conditions that govern the flow of energy and shared intermediates

Auxin, Jasmonic acid and Gibberellin have the same basic signalling pathway. Create a diagram of this...

Auxin, Jasmonic acid and Gibberellin have the same basic signalling pathway. Create a diagram of this generalized pathway that can be used to describe any of these hormones (this is another example of a useful study tool for the next midterm). Identify the proteins with functions similar to ARFs in jasmonate and gibberellin response. What is ubiquitin? What is the function of the proteasome and how does it know what protein to act on?

Describe in detail how the entire PKC pathway works, and diagram. Since we know the PKC pathway...

Describe in detail how the entire PKC pathway works, and diagram. Since we know the PKC pathway is activated by certain polypeptide hormones.

VAT (Philippines) 1. Make a diagram or flowchart 2. Start from a Value Added Tax-Exempt person...

VAT (Philippines) 1. Make a diagram or flowchart 2. Start from a Value Added Tax-Exempt person transacting to a Value Added Tax-registered person. From the Value Added Tax registered, two transactions happen 1) Export sale and 2)Local sale. 3. Compute the Input Value Added Tax, Output Value Added Tax and Value Added Tax payable in each transaction, if applicable 4. Presentations similar to real business transactions will be appreciated.

What is the overall “strategy” of fatty acid synthesis, and how does it compare with that...

What is the overall “strategy” of fatty acid synthesis, and how does it compare with that for fatty acid degradation? Explain.

Starting with a fatty acid located in the cytosol of the cell, explain “mechanistically” how an...

Starting with a fatty acid located in the cytosol of the cell, explain “mechanistically” how an iron deficiency may result in reduced acetyl CoA production from beta oxidation of palmitic acid

How do lactic acid homofermemtative pathway and heterofermentative pathway differ in their glycolytic pathways? Why do...

How do lactic acid homofermemtative pathway and heterofermentative pathway differ in their glycolytic pathways? Why do they differ in these pathways and what is the advantage of the two alternate glycolytic pathways vs. the classical EMP glycolytic pathway?

how to make benzoic acid

Question