What are the biological and radiological properties of xeon 133 and Gallium 67. For radiological imaging...

What are the biological and radiological properties of xeon 133 and Gallium 67. For radiological imaging with the gamma camera.

Expert Solution

Gallium 67 is a photon-emitting radiotracer which is used in the form of various salts like citrate and nitrate. Once administered, imaging may consist of planar (2 dimensional) , SPECT, and SPECT/CT acquisitions. Once injected it binds to plasma proteins (especially transferrin), and has a predilection to sites of inflammation. It binds to inflammatory proteins and thus it pools up at the sites of various inflammatory and granulomatous reactions.

Radionuclide profile

emits a spectrum of gamma rays (93, 185, 288, 394 KeV energy)
half life is about 78 hours
critical organ: colon
normal distribution is seen in the liver, bone marrow and spleen.

Xenon-133 is a radiopharmaceutical principally used when a performing VQ scan. Inhalation of this gas can also be used to assess cerebral blood flow.

photon energy: 81 KeV
physical half-life: 5.27 days
biological half-life: 30 seconds
normal distribution: lungs
- <15% of inhaled gas is absorbed
excretion: lungs
target organ: lungs

Xenon-133 is a fission product from uranium-235. The gas is normally supplied in a concentration of 5% with 95% carbon dioxide.

genius_generous answered 5 months ago

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