Question

1. the starting mass of your aspirin tablet(mg)

2. the amount of ASA recovered

3. the calculated mass of excipients/binders that were not recovered

4. the melting point('c) of your isolated ASA

5. What is the percent isolation of the active ingredient, ASA? Provide your % isolation calculation ( Note: percent isolation is mg of ASA recovered/ manufacturer mg stipulated*100)

6. Describe some observations you found fascinating. Discuss the purpose of acquiring a melting point and what it means to a budding scientist, like you! Discuss how we might have lost material in the experiment

This experiment is Isolation of ASA from an Aspirin Tablet

Aspirin = 325mg

mass of tablet= 376mg

1grain=64.8, contain 5grains

tare weight of Aluminum weighing= 411mg

154 ASA isolated, % isolation= actual/theoretical=154/325*100=47%

Answer 1

a) Aspirin is a trade name for acetylsalicylic acid,a common aanlgesic.
Acetylsaliicylic acid in a single aspirin tablet is 325mg ,yet the
tablet has a mass of 2.00 g.

Answer:The starting mass of
y0ur ASIRIN IS SINGLR - 325mg yet it has
the mass of 2.00mg.

b)Using the three analyses method of a U.S.P quality acetylsalicylic acid gave 100.1%,99.9%,99.6% recovery.In each case the salicylic acid content of
the recovered material was less than ).1 5%.

3)Excipients used in tablet formulation may be of two types
Those that help to impart satisfactory processing and compression charecteristics to the formulation.
Those that help to give additional desirable physical charecteristicsto the vompressed tablets.

4)The melting point of isolated aspirin is 138 - 140 C and the melting point regular range of salicylid acid starting materials is 158 - 161 C.If there are impurities in the sample
the melting point of the product will be lower than the range of pure aspirin.

5)The active ingredient in each tablet of Aspirin(acetylsalisylic acid).Pain releiver /fever reducer.The Inactive ingredients are carnauba wax,corn starch,hypromellose,powered cellulose,tricetin.