Question

1- What medicines contain ibuprofen and what is it used for? (2 pts)

2- Write the chemical name and the molecular formula for the structure. (2 pts)

3- If you want to check the purity of the compound, which technique would you use? (2 pts)

4- (i) How many chiral centers are present in the structure? (ii) Draw the stereoisomers and assign R and S configuration to the structures. (4 pts)

6- Briefly explain what a Polarimeter is. How can it be helpful to characterize the ibuprofen structure? What information/results can be observed using this instrument? (5 pts)

7- What information does IR spectroscopy provide to identify the ibuprofen structure? (5 pts)

8- (i) What is NMR technique? (ii) What kind of information can it provide for the characterization of ibuprofen? (5 pts)

Answer 1

1- What medicines contain ibuprofen and what is it used for? (2 pts)

Ans: Non steroidal anti-inflammatory drug contains ibuprofen. It is used as analgesic, antipyretic also.

2- Write the chemical name and the molecular formula for the structure. (2 pts)

Ans: The molecular formula is: C₁₃H₁₈O₂

The chemical name is 2-(4-Isobutylphenyl)propanoic acid,

Or

3- If you want to check the purity of the compound, which technique would you use? (2 pts)

Ans: We can check the purity of the compound by any of these techniques

a) Gas chromatography Mass spectroscopy (GC_MS)

b) NMR spectroscopy

4- (i) How many chiral centers are present in the structure? (ii) Draw the stereoisomers and assign R and S configuration to the structures. (4 pts)

Ans: One chiral carbon is present in the structure