Explanation of the
analysis:
Bioprosthetic heart
valves: These biomedical appliances came into
existence since mid 1960"s. They are made from biological tissues
got from porcine aortic valves or calf pericardium. These are safe
to be implanted as their function is found to be similar to that of
natural human aortic valve.
Analysis;
- The tissues removed from the donor
like porcine or calf, has to be properly cleaned, evenly sized,
maintained at a particular pH before implantation.
- The safe and gentle handling of the
tissue has to be administered to aviod damage.
- It is also important to clearly
analyze the tissue before using for implantation.
- Some of the tissues or device may
show pre implantation or post implantation effects.
- It has been reported that using of
mechanical heart valves can be durable but their long term use may
cause damage to certain age group.
- hence bioprosthetic heart valves
are made into thin fabric covering like stents which are long
lasting as animal or human tissue is used.
- Before implantation, it is
necessary to screen the patient for graft rejections.
- Blood group analysis must also be
done.
- Patient's age is also a major
criteria to be checked.
- Homograft is a method where the
patient's own tissue is taken and placed in the device. This could
be preferable only for children.
- Xenograft is carried out by using
animal tissue like porcine or calf pericardium along with some
metal alloy to make it a stent. This lasts for atleast 10 - 15
years.
- Bovine pericardial valve is also
used, where the stent is placed in the middle and after 10 years of
implantation the durability is equal to that of porcine.
- The average lifespan of BHV is upto
15 years.