Question

Discuss how the structure of Sulfafurazole is consistent with its spectra.

Answer 1

Sulfafurazole structure confirmation using more spectrum technics using

1.Mass spectrum we get Molecular weight of Compound

Sulfafurazole molecular weight - 267.30

Mass spectrum given mass - possitive peaks - 268

2.NMR Spectrum (proton and 13C) structure elucidation

!H NMR - 4 signals

2 methyl groups comes to arround -2.5ppm in singlet (6H)

aromatic protons comes to arround - 6.5 to 7.5ppm in doublet (4H)

primary amine comes to arround - 6 -to 6.2ppm in singlet (2H)

secondary amine comes to arround - 10 to 10.5ppm in singlet (1H)

13C NMR spectrum details givie photo copy

3.Elemental analysis

C - 49.43%

H - 4.90%

N - 15.72%

O - 17.96%

S - 11.99%

4.IR Spectrum (Functional group identification)

Generally amines comes to 3400 to 3000 Cm-1

Sulfafurazole different two amines there 1.primary amine another one is 2.secondary amine

so, IR spectrum different primary and secondary amines

primary amine comes to stretching 2 peaks arround (1.3400 - 3300 Cm-1 , 2.33000-3250 Cm-1)

secondary amine comes to only one band stretching arround ( 3350 - 3310 Cm-1)

bending only comes to primary amine 1650 - 1580 Cm-1

aromatic amine comes to arrount 1335 - 1250 Cm-1

NH wag common primary and secondary amine comes to 910 - 6660 Cm-1

SO2 comes to arround 1300-1100Cm-1

finally confirmed sulfafurazole structure