What are the contributions of glycolisis and citric acid cycle to the aerobic oxidation, how is...

What are the contributions of glycolisis and citric acid cycle to the aerobic oxidation, how is the proton motive force is generated?

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Expert Solution

In glycolysis the glucose is converted to pyruvate. Pyruvate can further undergo lactic acid fermentation or aerobic oxidation or alcoholic fermentation. By glycolysis some ATPs are produced and some NADH are also produced.

Further pyruvate gets converted to acetyl Co-A which enters Kreb' s cycle or citric acid cycle where it undergoes many chemical changes and ATPs, NADH and FADH2 are produced.

Further these NADH2 and FADH2 are dissociated by enzymes of electron transport change which are present on inner mitochondrial membrane. Upon dissociation electrons are released which are transferred to various ETS enzymes and at the same time H+ ions (protons) are transferred to inter membrane space of mitochondria. This generat a pH gradient. This pH gradient drives 'proton motive force'. Due to this force protons are transferred back to mitochondrial stroma because of which ATPase produce ATPs from ADPs.

gladiator answered 1 year ago

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