inThe citric acid cycle there are three reactions of the citric
acid cycle it's self that are regulated:
-citrate synthase which is where ATP inhibits in in
citeo
-isocitrate dehydrogenase: alosterrically activated by Ca2+
and ADP also is inhibited by NADH
- alpha ketoglutarate dehydrogenase which is where Ca2+
increases the rate of formation of succinyl-CoA
what would happen if all three of these reactions were not
present? what would happen if citrate synthase was not functioning,
what would happen...
Show the three reactions in the citric acid cycle in which NADH
is produced. Including the structures. None of these reactions
involves molecular oxygen (O2), but all three reactions are
strongly inhibited by anaerobic conditions. Explain why.
In the citric acid cycle, malate is oxidized to oxaloacetate by
the enzyme malate dehydrogenase, which uses NAD+ as an electron
acceptor. In cells, the ratio of [NAD+]/[NADH] is kept very high.
Given the following standard reduction potentials, explain why it
is so important for cells to maintain this ratio. Justify your
answer with words, equations and diagrams.
oxaloacetate + 2H+ + 2e- -> malate
E°red= -0.166 V
NAD+ + H+ + 2e- > NADH
E°red= -0.320
Which reactions in the citric acid cycle are irreversible under
physiological conditions, and for each of these reactions, explain
why the reaction is irreversible.
Intermediates of the citric acid cycle can participate in which
of the following metabolic pathways?
Group of answer choices
gluconeogenesis
fatty acid anabolism
heme biosynthesis
amino acid anabolism
all of the above
In which process(es) are electron carriers reduced? options:
Both Lactic acid fermentation and Citric acid cycle
Neither Lactic acid fermentation nor Citric acid cycle
Citric acid cycle in mitochondria
Lactic acid fermentation
What role does the citric acid cycle play in amino acid
metabolism?a. breakdown of glucogenic amino acids feeds metabolites into
the citric acid cycleb. amino acid synthesis often relies on intermediates of the
citric acid cyclec. breakdown of ketogenic amino acids feeds metabolites into the
citric acid cyclea, b, & ca & b