Question

In: Biology

1. What is a glycoproteins? 2. Where are they found in human cells?

 
1. What is a glycoproteins?
2. Where are they found in human cells?
3. List two important functions.
4. How are glycoproteins manufactured in a cell?

Solutions

Expert Solution

Ans .(1) Glycoproteins are proteins which contain oligosaccharide chains (glycans ) covalently attached to amino acid side-chains.

Ans .(2) Glycoproteins are found on the surface of the lipid bilayer of cell membranes.

Ans .(3) Glycoproteins in the cell membrane are very important for cell - to- cell recognition and adhesion, as well as serving as receptors for other types of molecules.

Ans .(4) The protein component of glycoprotein is assembled on the surface of the rough endoplasmic reticulum by the sequential addition of amino acids, creating a linear polymer of amino acids called polypeptide.

O-linked glycoproteins are synthesized by the addition of sugar residues to the hydroxyl side chain of serine or threonine residues in polypeptides in the Golgi apparatus.

N-linked glycoproteins are synthesized and modified within two membrane-bound organelles in the cell, the rough endoplasmic reticulum, and the Golgi apparatus. N - linked glycoproteins are almost always attached to the nitrogen atom of asparagine side chain.


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