In: Nursing

In looking at exenatide, how is this drug administered? How is it supplied? What type of diabetic is this drug used for? How does it work? What are 3 priority teaching points?

**ANSWER.**

***
Administration of Exenatide.**

* Exenatide is
administered through **subcutaneous route.**

* It is administered one hour before the begining of first and

last meal of the day.

* **Supply of
Exenatide.**

* It is
supplied as **prefilled pens or vial** containing
exenatide power

for subcutaneous injection.

***
Use.**

* Exenatide used for
treatment of **Type 2 diabetes melitus.**

* **Three
priority teaching points.**

* Teaching about the importance of taking meal after exenatide

injection to avoid hypoglycemia.

* Educate the patient about how to prepare and inject exenatide

during self administration.

* Teach the patient to observe the colour of suspension before

injection and disposal methods if colour change occur.

Veronal, a barbiturate drug, is generally administered as its
sodium salt. What is the pH of a solution of
NaC8H11N2O3 that
contains 10. mg of the drug in 250 mL of solution? For veronal,
HC8H11N2O3, the
value
of Ka is 3.7 x 10-8.

A drug with a half-life of 15 hours is administered by
continuous intravenous infusion. How long will it take for the drug
to reach 75% of its final steady-state level?

A new drug cures 70 % of the patients to whom it is
administered. It is given to 28 patients. Find the probabilities
that among these patients, the following results occur. Use the
normal distribution approximation to the binomial distribution.
(a) Exactly 22 are cured.
(b) All are cured.
(c) No one is cured.
(d)14 or fewer are cured.

Pepto- Bismol
How the drug is supplied and given (dosage form, strength,
frequency, and ROA), how the drug works (MOA). Then, describe the
possible side effects with corresponding warning labels. Speak of
adverse reactions and any special considerations while taking this
medication. Do you have it in your medicine cabinet? Why?

What does it mean for a drug to be flow-limited? What type of
drug is more likely to be flow limited?
How does fitness affect pharmacokinetics?
How are drugs with a long half life and duration of action
affected by mild exercise?
How does higher intensity of exercise affect
pharmacodynamics?
How could exercise effect the therapeutic window?
What are up and down regulation?

Name the route of drug administration from its description
below:
Drug is administered via suppository or fluid into the anus
Drug is administered via vapor or gas into the nose or mouth
Drug is administered under the tongue
Drug is applied locally on skin or mucous membrane
Drug is given by mouth and absorbed through the stomach or
intestine
Drug is injected via syringe under the skin, into a vein,
muscle, or cavity
Matching:...

20. Calculate the total dose in cubic centimeters of a drug, to
be administered SQ to a patient weighing 12 pounds. The
concentration of the drug is 2mg/ml and the dosage rate is 10mg per
kg._____________
21. Calculate the total dose in cubic centimeters of a drug, to
be administered SQ to a patient weighing 105 pounds. The
concentration of the drug is 100mg/ml and the dosage rate is 15mg
per kg._____________

The drug Prevnar is a vaccine meant to prevent meningitis. It is
typically administered to infants. In clinical trials, the vaccine
was administered to 710 randomly sampled infants between 12 and 15
months of age. Of the 710 infants, 121 experienced a loss of
appetite. Is this significant evidence to conclude that the
proportion of infants who receive Prevnar and experience a loss of
appetite is different than 0.135 which is the proportion of
children who experience a loss of...

19. Calculate the total dose in cubic centimeters of a drug, to
be administered IV to a patient weighing 81 pounds. The
concentration of the drug is 20mg/ml and the dosage rate is 11mg
per kg._____________
A. Calculate the total dose in cubic centimeters of a drug, to
be administered SQ to a patient weighing 17 pounds. The
concentration of the drug is 2mg/ml and the dosage rate is 10mg per
kg._____________
B. Calculate the total dose in cubic centimeters...

A drug for IV infusion is supplied as a 4 mL vial with a
concentration of 2.5 mg /mL. the contents of the vial are
transferred into an infusion bag to make a final volume of 1000 mL.
The infusion is to run for a total of 120 minutes with a flow rate
of 30 mL /hour. How much drug will be delivered?

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