Question

In: Biology

Which of the following is NOT an epigenetic stimulus/marker used to package DNA? Select one: -...

Which of the following is NOT an epigenetic stimulus/marker used to package DNA?

Select one:

- Ubiquitination

- Methylation

- Phosphorylation

- Acetylation

Solutions

Expert Solution

  • The change or alteration in the structure of DNA or chromatin in eukaryotes, including, DNA methylation, DNA Acetylation, Chromatin structure changes, remodeling, histone modification, is termed as epigenetics.
  • Chromosome is organized form of DNA in eukaryotic cells.
  • The chromatin is organized with the help of histone proteins to form the nucleosome.
  • About 146-147 bp DNA length is tightly wrapped around octameric core histones (Two copies of each H2A, H2B, H3 and H4 histone proteins).
  • These nucleosome cores are separated by linker DNA, which are associated with Histone H1.
  • Modification of histone at the basic N-terminal amino acid tails causes the amino acid tails to protrude out of their specific nucleosome and interact with adjacent nucleosomes. This alters the interaction of DNA and histone proteins, resulting in DNA to loosen or become more tightly coiled with histone.

Ubiquination is mainly involved in DNA repair.

Answer:  Ubiquination


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