Part A: Zwitterionic Form Two structures of alanine can be drawn that have a net charge...

Part A: Zwitterionic Form

Two structures of alanine can be drawn that have a net charge of zero, but the predominant form of alanine at its pI is zwitterionic. Why is alanine predominantly zwitterionic rather than completely uncharged at its pI? What percent (to one significant figure) of alanine molecules would be in the completely uncharged form at the pI? Hint: pK₁ of alanine is 2.35 and pK₂ is 9.87.

(answer is NOT .24%)

Part B: Hardy-Weinberg

The following question is intended to complement our discussion of inherited diseases, a topic that was introduced when the molecular basis of sickle-cell anemia was explored in a previous chapter. Here goes: In a population that is in Hardy-Weinberg equilibrium, 9.0% of the individuals show the recessive trait. What is the frequency (expressed as a percent to the nearest ones) of the heterozygous individuals (for this trait) in the population? Assume the alleles are autosomal.

Part C - Surface Area to Volume

Derive an expression that relates the surface area (SA) of a cylinder to the volume (V) of a cylinder (i.e., SA:V). Then derive an expression that relates the SA:V of one cylinder to that of another cylinder and use this relationship to compare the SA:V of a ~cylinder-shaped Escherichia coli to the SA:V of a ~cylinder-shaped Bacillus megaterium. E. coli is 2 μm in length and 0.5 μm in diameter whereas B. megaterium is 4 μm in length and 1.5 μm in diameter. Report your answer to the nearest tenths. For example, if your answer was 6.9:1 you would just report 6.9, the "to one" part is understood.

Expert Solution

queen_honey_blossom answered 2 years ago

Two structures of alanine can be drawn that have a net charge of zero, but the...

Two structures of alanine can be drawn that have a net charge of zero, but the predominant form of alanine at its pI is zwitterionic. Why is alanine predominantly zwitterionic rather than completely uncharged at its pI? What percent (to one significant figure) of alanine molecules would be in the completely uncharged form at the pI? Hint: pK1 of alanine is 2.35 and pK2 is 9.87.

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