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In: Biology

We know that Cyclins are critical regulators of promoting the cell through the stages of the...

We know that Cyclins are critical regulators of promoting the cell through the stages of the cell cycle. And also their mis regulation could lead to cancerous growth (or no division at all).

Please help by describing the following...

1) the ways that cyclin/cdk complexes can be regulated

2) the role that Rb (retinoblastoma) and p53 have in cell cycle control (as they relate to cyclins).

Please use more than 2 sentences to explain! The more information the better to help me understand. Thanks a lot!

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