What are the critical questions left (We still don’t know)regarding rqc2p (Rqc2p Protein Synthesis) and...

What are the critical questions left (We still don’t know) regarding rqc2p (Rqc2p Protein Synthesis) and 60s ribosomal subunits mediate mRNA-independent elongation of nascent chains?

Expert Solution

rqc2p is a component of RQC ( Ribosomes quality control complex).

During the stalled translation, dissociation of the 40s subunit of ribosomes is induced. After that the rqc2p is recruited to the 60s site of ribosomes.

rqc2p displaces the new gene towards the exit channel. After that it recruits the charged t-RNA to the A site of the ribosomes and directs the elongation of the nascent chain.

Comment for further assistance.

gladiator answered 2 years ago

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