Question

In: Chemistry

Which of the following does not result from accumulation of partially degraded gangliosides? Phenylketourea Tay-Sachs disease...

Which of the following does not result from accumulation of partially degraded gangliosides?

Phenylketourea
Tay-Sachs disease
Niemann-Pick disease
Gaucher's disease

Solutions

Expert Solution

Correct option: Phenylketourea

The membranes of the human nervous system contain at least 15 different gangliosides for which no function is yet known. However, it is clearly important that the synthesis and breakdown of these compounds be tightly regulated; derangements in the metabolism of cerebrosides and gangliosides underlie the devastating effects of several human genetic diseases, including Tay-Sachs, Gaucher's disease and Niemann-Pick diseases.

The following figure is reproduced from my reference text book as i cannot make such a beautiful image, otherwise this answer does not fulfil its aim.

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queen_honey_blossom answered 2 years ago
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