Question

In: Anatomy and Physiology

1) Outline the primary mechanism of control of the thyroid gland via the hypothalamus and anterior...

1) Outline the primary mechanism of control of the thyroid gland via the hypothalamus and anterior pituitary. Include all hormones involved.

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Answer

Thyroid gland is an endocrine gland that releases hormones called thyroxine (T4) and triiodothyronine (T3). TheSe hormones mainly functions to regulate all the metabollic processes in the body.

Secretion of thyroid gland is regulated by a feedback control mechanism.

  • When levels of T3 and T44 are low in blood, hypothalamus releases a regulatory hormone called thyrotropin releasing hormone (TRH).
  • TRH acts on anterior pituitary gland and stimulates the release of a tropic hormone called thyroid stimulating hormone (TSH).
  • TSH acts on thyroid gland and stimulate release of thyroxine (T4) and triiodothyronine (T3).
  • This increases the levels of T3 and T4 in the blood.
  • When levels of T3 and T4 in the blood increases above normal range, these hormones send a negative feedback signal to the hypothalamus in order to inhibit secretion of TRH.
  • As a result anteior pituitary also inhibits TSH secretion.
  • Due to lack of TSH stimulation, thyroid gland inhibits production of T3 and T4.
  • The levels of thyroid hormone decreases to normal range.

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